Article
The Simpson-Golabi-Behmel gene, GPC3, is not involved in sporadic Wilms tumorigenesis.
American journal of medical genetics. Part A - 15 Sept 2003
Gillan Tanya L, Hughes Rhiannon, Godbout Roseline, Grundy Paul E
Abstract excerpt
Many genes have been implicated in Wilms tumor; however, only one gene, WT1, has a proven role in the development of this embryonal tumor. Wilms tumor occurs in a number of congenital syndromes including the Simpson-Golabi-Behmel syndrome (SGBS) which has phenotypic overlap with another Wilms tumor-predisposing syndrome Wiedemann-Beckwith syndrome. The putative function and expression pattern of the SGBS gene,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
