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Article

Somatic glypican 3 (GPC3) mutations in Wilms' tumour.

British journal of cancer - 17 Jun 2002

White G R M, Kelsey A M, Varley J M, Birch J M

Abstract excerpt

Tumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumour development.

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Source

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Identifiers

PMID: 12085187
DOI: 10.1038/sj.bjc.6600417
PMCID: PMC2375433

Genes

GPC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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