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Article

Physiological studies of Escherichia coli strain MG1655: growth defects and apparent cross-regulation of gene expression.

Journal of bacteriology - 1 Sept 2003

Soupene Eric, van Heeswijk Wally C, Plumbridge Jacqueline, Stewart Valley, Bertenthal Daniel, Lee Haidy, Prasad Gyaneshwar, Paliy Oleg, Charernnoppakul Parinya, Kustu Sydney

Abstract excerpt

Escherichia coli strain MG1655 was chosen for sequencing because the few mutations it carries (ilvG rfb-50 rph-1) were considered innocuous. However, it has a number of growth defects. Internal pyrimidine starvation due to polarity of the rph-1 allele on pyrE was problematic in continuous culture...

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Identifiers

PMID: 12949114
DOI: 10.1128/JB.185.18.5611-5626.2003
PMCID: PMC193769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12949114-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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