Article
Latent hepatitis B virus (HBV) infection and HBV DNA integration is associated with further transformation of hepatoma cells in vitro.
ALTEX - 1 Jan 2003
Favre Daniel, Petit Marie-Anne, Trépo Christian
Abstract excerpt
Hepatitis B virus (HBV) is the major cause of chronic liver disease and hepatocellular carcinoma in the world, with more than 400 million people infected worldwide. To date, there is no reliable model for the study of the many aspects of HBV infection, despite the use of the chimpanzee. Although several alternative methods have been previously developed for the in vitro study of HBV infection, there is still an...
Topics
- Animal Testing Alternatives
- Blotting, Southern
- Carcinoma, Hepatocellular
- Cell Line
- Cell Transformation, Viral
- Culture Media
- DNA, Viral
- Dexamethasone
- Flow Cytometry
- Hepatitis B
- Hepatitis B Surface Antigens