Article
Atypical teratoid/rhabdoid tumors and choroid plexus tumors: when genetics "surprise" pathology.
Brain pathology (Zurich, Switzerland) - 1 Jul 2003
Gessi Marco, Giangaspero Felice, Pietsch Torsten
Abstract excerpt
Atypical teratoid/rhabdoid tumor (ATRT) and choroid plexus tumors (CPT) represent, so far, 2 well defined types of CNS neoplasm on the basis of their histological features and clinical presentation (10). While CPTs are intraventricular epithelial tumors arising from choroid plexus epithelium, the cellular origin of ATRTs is still unknown. Inactivating mutations of the hSNF5/INI-1 gene located in the chromosomal...
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