Article
Atypical teratoid/rhabdoid tumor arising in a ganglioglioma: genetic characterization.
The American journal of surgical pathology - 1 Dec 2011
Kleinschmidt-DeMasters B K, Birks Diane K, Aisner Dara L, Hankinson Todd C, Rosenblum Marc K
Abstract excerpt
Atypical teratoid/rhabdoid tumor (AT/RT) is an uncommon, aggressive, embryonal pediatric brain tumor that almost always develops de novo and does not arise within, or evolve from, other brain tumor types. Although rhabdoid morphology can be seen in other tumor types, these are phenotypic mimics and, with only rare exceptions, do not manifest the INI-1 deletion at the 22q11.2 locus or the INI-1 nuclear protein...
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