Article
[Role of different isoforms of nitric oxide synthase in development of tumor mutants in Drosophila melanogaster].
Ontogenez - 1 Jan 2000
Dzhansugurova L B, Bekmanov B O, Bersimbaev R I
Abstract excerpt
We studied the role of nitric oxide synthase during tumor growth in oncovirus-induced tumor mutants of Drosophila melanogaster. The lines with different capacity for malignancy differed reliably in the level of enzymatic activity. It was shown using specific inhibitors of neuronal and inducible isoforms that the neuronal isoform was not involved in tumor formation, while the inducible one appears to play an...
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