Article
Association between HPV 16/18 infection and expression of P53 protein in laryngeal papillomas.
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao - 1 Jan 1999
Chu H, Reyt E
Abstract excerpt
To understand the relationship between expression of P53 protein and HPV16/18 infection in laryngeal papillomas, PCR and immunohistochemical techniques were used to examine the paraffin-embedded tissue samples of laryngeal papillomas from 35 subjects. HPV 16/18-DNA was found in 24 cases of laryngeal papillomas (68.8%). Overexpression of P53 protein was detected in 19 cases (54.3%). Both HPV16/18-DNA and...
Topics
- Human papillomavirus 16
- Human papillomavirus 18
- Humans
- Laryngeal Neoplasms
- Mutation
- Papilloma
- Papillomavirus Infections
- Tumor Suppressor Protein p53
