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Article

Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae.

The Journal of biological chemistry - 31 Oct 2003

Chan Sherwin Y, Appling Dean R

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, used to methylate homocysteine in methionine biosynthesis. Methionine can be activated by ATP to give rise to the universal methyl donor, S-adenosylmethionine (AdoMet). Previously, a chimeric MTHFR (Chimera-1) comprised of the yeast Met13p N-terminal catalytic domain and the...

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Source

Identifiers

PMID: 12937179
DOI: 10.1074/jbc.M308696200

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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