Article
Polymorphisms in the SEEK1 and SPR1 genes on 6p21.3 associate with psoriasis in the Swedish population.
Experimental dermatology - 1 Aug 2003
Holm Sofia J, Carlén Lina M, Mallbris Lotus, Ståhle-Bäckdahl Mona, O'Brien Kevin P
Abstract excerpt
Psoriasis is a chronic skin disease that results in red and scaly lesions. Several psoriasis susceptibility loci have been identified across the genome, of which PSORS1 on 6p21.3 is predominant. There is an ongoing debate regarding whether the HLA-C allele, Cw*0602, can be considered the major pr...
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