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Article

LMNA mutations in atypical Werner's syndrome.

Lancet (London, England) - 9 Aug 2003

Chen Lishan, Lee Lin, Kudlow Brian A, Dos Santos Heloisa G, Sletvold Olav, Shafeghati Yousef, Botha Eleanor G, Garg Abhimanyu, Hanson Nancy B, Martin George M, Mian I Saira, Kennedy Brian K, Oshima Junko

Abstract excerpt

BACKGROUND: Werner's syndrome is a progeroid syndrome caused by mutations at the WRN helicase locus. Some features of this disorder are also present in laminopathies caused by mutant LMNA encoding nuclear lamin A/C. Because of this similarity, we sequenced LMNA in individuals with atypical Werner...

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Source

Identifiers

PMID: 12927431
DOI: 10.1016/S0140-6736(03)14069-X

Genes

LMNA
WRN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12927431-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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