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Article

Biological effect of varying peptide binding affinity to the BoLA-DRB3*2703 allele.

Genetics, selection, evolution : GSE - 1 Jan 2003

Alizadeh Zahra, Karrow Niel, Mallard Bonnie A

Abstract excerpt

MHC class I and II molecules are immunoregulatory cell surface glycoproteins, which selectively bind to and present antigenic peptides to T-lymphocytes. Murine and human studies show that variable peptide binding affinity to MHC II molecules influences Th1/Th2 responses by inducing distinctive cytokine expression. To examine the biological effects of peptide binding affinity to bovine MHC (BoLA), various self...

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Identifiers

PMID: 12927080
DOI: 10.1186/1297-9686-35-S1-S51
PMCID: PMC3238229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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