Article
Genome-wide linkage disequilibrium mapping of hypertension in Japan.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jul 2003
Wu Zhihong, Nakura Jun, Abe Michiko, Jin Jing-Ji, Yamamoto Miyuki, Chen Yusen, Tabara Yasuharu, Yamamoto Yoshikuni, Igase Michiya, Bo Xiao, Kohara Katsuhiko, Miki Tetsuro
Abstract excerpt
Hypertension is a common, complex phenotype resulting from the interaction between genetic and environmental factors. To select candidate regions potentially responsible for hypertension, we are conducting a genome-wide linkage disequilibrium (LD) mapping of hypertension using dinucleotide repeat markers in 146 hypertensive and 136 normotensive subjects. Although the LD mapping is still underway, 19 alleles of 15...
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