Article
Sarcoglycans in vascular smooth and striated muscle.
Trends in cardiovascular medicine - 1 Aug 2003
Wheeler Matthew T, McNally Elizabeth M
Abstract excerpt
Sarcoglycans are transmembrane proteins important in the maintenance of proper muscle function. Together, the sarcoglycans form a heteromeric complex that interacts with dystrophin, dystroglycan, and filamin C to form a mechanosignaling complex. Mutations in the genes encoding sarcoglycan can produce cardiomyopathy and muscular dystrophy. Studies of patients and animal models have emphasized the variability in...
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