Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

zeta-Sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy

1 Sept 2002

Abstract excerpt

The dystrophin glycoprotein complex (DGC) is found at the plasma membrane of muscle cells, where it provides a link between the cytoskeleton and the extracellular matrix. A subcomplex within the DGC, the sarcoglycan complex, associates with dystrophin and mediates muscle membrane stability. Mutations in sarcoglycan genes lead to muscular dystrophy and cardiomyopathy in both humans and mice. In invertebrates,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Muscle Physiology and Disorders

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 12189167
DOI: 10.1093/hmg/11.18.2147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

zeta-Sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophyPMID 12189167Read ↗

Differential requirement for individual sarcoglycans and dystrophin in the assembly and function of the dystrophin-glycoprotein complex.Semantic proximity Read ↗

Sarcoglycans in muscular dystrophy.Semantic proximity Read ↗

Human epsilon-sarcoglycan is highly related to alpha-sarcoglycan (adhalin), the limb girdle muscular dystrophy 2D gene.Semantic proximity Read ↗

Sarcoglycanopathies: molecular pathogenesis and therapeutic prospectsSemantic proximity Read ↗

ε-Sarcoglycan, a Broadly Expressed Homologue of the Gene Mutated in Limb-Girdle Muscular Dystrophy 2DSemantic proximity Read ↗

Identification of functional domains in sarcoglycans essential for their interaction and plasma membrane targeting.Semantic proximity Read ↗

Sarcoglycan Isoforms in Skeletal MuscleSemantic proximity Read ↗

Overexpression of gamma-sarcoglycan induces severe muscular dystrophy. Implications for the regulation of Sarcoglycan assembly.Semantic proximity Read ↗

ε-Sarcoglycan Replaces α-Sarcoglycan in Smooth Muscle to Form a Unique Dystrophin-Glycoprotein ComplexSemantic proximity Read ↗

Mutations in the delta-sarcoglycan gene are a rare cause of autosomal recessive limb-girdle muscular dystrophy (LGMD2).Semantic proximity Read ↗

Molecular and genetic characterization of sarcospan: insights into sarcoglycan-sarcospan interactionsSemantic proximity Read ↗

From dystrophinopathy to sarcoglycanopathy: evolution of a concept of muscular dystrophy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.