Article
α-Smooth Muscle Actin and ACTA2 Gene Expressions in Vasculopathies.
Brazilian journal of cardiovascular surgery - 1 Jan 2000
Yuan Shi-Min
Abstract excerpt
α-smooth muscle actin, encoded by ACTA2 gene, is an isoform of the vascular smooth muscle actins, typically expressed in the vascular smooth muscle cells contributing to vascular motility and contraction. ACTA2 gene mutations cause a diversity of diffuse vasculopathies such as thoracic aortic aneurysms and dissections as well as occlusive vascular diseases, including premature coronary artery disease and ischemic...
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