Article
Sarcoglycans in muscular dystrophy.
Microscopy research and technique - 1 Jan 2000
Hack A A, Groh M E, McNally E M
Abstract excerpt
Muscular dystrophy is a heterogeneous genetic disease that affects skeletal and cardiac muscle. The genetic defects associated with muscular dystrophy include mutations in dystrophin and its associated glycoproteins, the sarcoglycans. Furthermore, defects in dystrophin have been shown to cause a disruption of the normal expression and localization of the sarcoglycan complex. Thus, abnormalities of sarcoglycan are...
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