Article
Genomic and genetic alterations influence the progression of gastric cancer.
World journal of gastroenterology - 21 Jan 2011
Nobili Stefania, Bruno Lorenzo, Landini Ida, Napoli Cristina, Bechi Paolo, Tonelli Francesco, Rubio Carlos A, Mini Enrico, Nesi Gabriella
Abstract excerpt
Gastric cancer is one of the leading causes of cancer-related deaths worldwide, although the incidence has gradually decreased in many Western countries. Two main gastric cancer histotypes, intestinal and diffuse, are recognised. Although most of the described genetic alterations have been observed in both types, different genetic pathways have been hypothesized. Genetic and epigenetic events, including 1q loss...
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