Article
Mixture distribution analysis of phenotypic markers reflecting HFE gene mutations.
Blood - 15 Dec 2003
McLaren Christine E, Li Kuo-Tung, Garner Chad P, Beutler Ernest, Gordeuk Victor R
Abstract excerpt
The goal of this study was to determine whether statistical modeling of population data for a phenotypic marker could reflect a major locus gene defect. Identifying mutations in the HFE gene makes it possible to assess the association between transferrin saturation (TS) subpopulations and HFE mutations. Data were analyzed from 27 895 white patients who attended a health appraisal clinic and who had TS and common...
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