Article
[Linkage disequilibrium analysis of the single nucleotide polymorphisms in the PRKCZ gene].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Oct 2002
Sun Hong-xia, Du Wei-nan, Li Yun-feng, Zuo Jin, Wu Guo-dong, Shen Yan, Qiang Bo-qin, Yao Zhi-jian, Hang Jian-mei, Luo Hui-yuan, Wang Heng, Huang Wei, Chen Zhu, Fang Fu-de
Abstract excerpt
OBJECTIVE: To search for the disease-associated haplotype in the PRKCZ gene, a susceptibility gene for type 2 diabetes in Han population of North China, by case-control study and linkage disequilibrium (LD) analysis using single nucleotide polymorphisms (SNPs). METHODS: SNPs located in the PRKCZ gene were chosen from public SNP domain by bioinformatic methods and single base extension (SBE) method was used to...
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