Article
Occurrence of an activated, profibrotic pattern of gene expression in lung CD8+ T cells from scleroderma patients.
Arthritis and rheumatism - 1 Aug 2003
Luzina Irina G, Atamas Sergei P, Wise Robert, Wigley Fredrick M, Choi Jung, Xiao Hui Qing, White Barbara
Abstract excerpt
OBJECTIVE: Pulmonary fibrosis is a major cause of death in scleroderma patients. Previous studies have shown an increase in CD8+ T cells in the lungs of scleroderma patients. In the present study, we sought to determine whether activated CD8+ T cells contribute to pulmonary fibrosis in scleroderm...
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