Article
Altered immune phenotype in peripheral blood cells of patients with scleroderma-associated pulmonary hypertension.
Clinical and translational science - 1 Oct 2010
Risbano Michael G, Meadows Christina A, Coldren Christopher D, Jenkins Tiffany J, Edwards Michael G, Collier David, Huber Wendy, Mack Douglas G, Fontenot Andrew P, Geraci Mark W, Bull Todd M
Abstract excerpt
Pulmonary arterial hypertension is a common and fatal complication of scleroderma that may involve inflammatory and autoimmune mechanisms. Alterations in the gene expression of peripheral blood mononuclear cells have been previously described in patients with pulmonary arterial hypertension. Our goal is to identify differentially expressed genes in peripheral blood mononuclear cells in scleroderma patients with...
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