Article
Analysis of single nucleotide polymorphisms in uridine/cytidine kinase gene encoding metabolic enzyme of 3'-ethynylcytidine.
Nucleic acids research. Supplement (2001) - 1 Jan 2002
Hasegawa Takako, Futagami Michiko, Kim Hey-Sook, Matsuda Akira, Wataya Yusuke
Abstract excerpt
We investigated single nucleotide polymorphisms (SNPs) in uck2 gene encoding metabolic enzyme of 3'-ethynylcytidine (ECyd) which were associated with drug response of ECyd, and the newly synthesized antitumor ribonucleoside analog. We analized that on exon-intron junction and exon region to affec...
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