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Article

Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cells.

Biochemical and biophysical research communications - 22 Aug 2003

Yasuda Jun, Tsuchiya Akira, Yamada Tesshi, Sakamoto Michiie, Sekiya Takao, Hirohashi Setsuo

Abstract excerpt

Deregulation of Wnt/beta-catenin signaling is thought to play a critical role in human carcinogenesis. Nemo-like kinase (NLK) is an evolutionarily conserved serine/threonine kinase that suppresses beta-catenin/T-cell factor (TCF) complex transcriptional activity through phosphorylation of TCF. Si...

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Source

Identifiers

PMID: 12901858
DOI: 10.1016/s0006-291x(03)01343-3

Genes

NLK
DLD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12901858-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cells.PMID 12901858Read ↗

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