Article
Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia.
Transfusion - 1 Feb 2018
Ouchari Mouna, Srivastava Kshitij, Romdhane Houda, Jemni Yacoub Saloua, Flegel Willy Albert
Abstract excerpt
BACKGROUND: With more than 460 RHD alleles, this gene is the most complex and polymorphic among all blood group systems. The Tunisian population has the largest known prevalence of weak D Type 4.0 alleles, occurring in one of 105 RH haplotypes. We aimed to establish a rationale for the transfusion strategy of weak D Type 4.0 in Tunisia. STUDY DESIGN AND METHODS: Donors were randomly screened for the serologic...
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