Article
Early mitochondrial dysfunction occurs in motor cortex and spinal cord at the onset of disease in the Wobbler mouse.
Experimental neurology - 1 Aug 2003
Dave Kunjan R, Bradley Walter G, Pérez-Pinzón Miguel A
Abstract excerpt
The Wobbler mouse is recognized as an animal model for motoneuron disease that exhibits motoneuron pathology. We have recently demonstrated the occurrence of mitochondrial dysfunction in the Wobbler mouse brain. The aim of the present study was to evaluate whether mitochondrial dysfunction occurr...
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