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Article

Polyglutamine-expanded ataxin-1 recruits Cu/Zn-superoxide dismutase into the nucleus of HeLa cells.

Biochemical and biophysical research communications - 1 Aug 2003

Kim Sung-Jo, Kim Tae-Soo, Kim Ick Young, Hong Sunghoi, Rhim Hyangshuk, Kang Seongman

Abstract excerpt

Spinocerebellar ataxia 1 (SCA1) is an inherited neurodegenerative disorder caused by expansion of the polyglutamine stretch in ataxin-1, the SCA1 gene product. Polyglutamine expansion leads to the aggregation of ataxin-1 proteins. Superoxide dismutases (SODs) are involved in the pathogenesis of o...

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PMID: 12893274
DOI: 10.1016/s0006-291x(03)01241-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12893274-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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