Article
Association between thrombin-activatable fibrinolysis inhibitor (TAFI) and clinical outcome in patients with unstable angina pectoris.
Thrombosis and haemostasis - 1 Jul 2003
Brouwers Geert-Jan, Leebeek Frank W G, Tanck Michael W T, Wouter Jukema J, Kluft Cornelis, de Maat Moniek P M
Abstract excerpt
Decrease of fibrinolytic potential is considered to be a risk factor for arterial thrombosis. The recently described thrombin-activatable fibrinolysis inhibitor (TAFI) attenuates fibrinolysis by cleaving of the C-terminal lysine residues from fibrin, thereby inhibiting tPA mediated plasminogen activation. The role of plasma TAFI antigen (Ag) levels and gene polymorphisms in arterial thrombosis is still not...
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