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Article

Engineering regulatory elements for conditionally-replicative adeno-viruses.

Current gene therapy - 1 Aug 2003

Haviv Yosef S, Curiel David T

Abstract excerpt

Virus-mediated oncolysis is a rapidly growing field with the potential to dramatically alter the future of cancer therapy. Replication-selective viruses are superior to non-replicating vectors in several aspects, such as the amplification of the initial low-dose viral inoculum up to 10(3)-10(3)-fold, lateralization into neighboring cells, introduction of novel cell killing mechanisms, and a potential for a safe...

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Identifiers

PMID: 12871022
DOI: 10.2174/1566523034578311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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