Article
Histological improvements after a three-year lamivudine therapy in patients with chronic hepatitis B in whom YMDD mutants did not or did develop.
Intervirology - 1 Jan 2003
Suzuki Yoshiyuki, Arase Yasuji, Ikeda Kenji, Saitoh Satoshi, Tsubota Akihito, Suzuki Fumitaka, Kobayashi Masahiro, Akuta Norio, Someya Takashi, Miyakawa Yuzo, Kumada Hiromitsu
Abstract excerpt
OBJECTIVE: The long-term effects of lamivudine and the influence of YMDD mutants on the histology of chronic hepatitis B are not known. METHODS: 3-year lamivudine therapy was given to 16 patients with chronic hepatitis B. YMDD mutants did not develop in 9 patients (group A), while they appeared i...
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