Article
Histological outcome during long-term lamivudine therapy.
Gastroenterology - 1 Jan 2003
Dienstag Jules L, Goldin Robert D, Heathcote E Jenny, Hann H W L, Woessner Mary, Stephenson Sally L, Gardner Stephen, Gray D Fraser, Schiff Eugene R
Abstract excerpt
BACKGROUND & AIMS: One year of lamivudine for chronic hepatitis B results in histologic improvement. We aimed to assess the histological impact of longer-term treatment. METHODS: Sets of 3 liver biopsies, from 63 patients before and after 1 year of randomized lamivudine treatment and after 2 years of further open-label treatment, were assigned Histologic Activity Index scores under code. RESULTS: At the end of...
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