Article
[Structural analysis of the PKR-binding region of HCV 1b samples from patients with chronic hepatitis C and the correlation with IFN-sensitivity].
Orvosi hetilap - 15 Jun 2003
Gervain Judit, Czibula Agnes, Simon Judit, Kalmár Tibor
Abstract excerpt
INTRODUCTION: 91.5% of all chronic HCV infections are of 1b-type in Hungary. Japanese researchers found a correlation between the outcome of interferon (IFN) therapy and the structure of the PKR-Binding Region (aa: 2209-2274) of the viral NS5A domain, especially a particular subsection of the PKR...
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