Article
Evaluation of the editing process in human immunodeficiency virus type 1 genotyping.
Journal of clinical microbiology - 1 Jul 2003
Huang Diana D, Eshleman Susan H, Brambilla Donald J, Palumbo Paul E, Bremer James W
Abstract excerpt
Sequencing-based human immunodeficiency virus type 1 (HIV-1) genotyping assays require subjective interpretation (editing) of sequence data from multiple primers to form consensus sequences and identify antiretroviral drug resistance mutations. We assessed interlaboratory variations in editing and their impact on the recognition of resistance mutations. Six samples were analyzed in a central laboratory by using a...
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