Article
Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas.
Journal of neuropathology and experimental neurology - 1 Jun 2003
McManamy Charles S, Lamont Jayne M, Taylor Roger E, Cole Michael, Pearson Andrew D J, Clifford Steven C, Ellison David W
Abstract excerpt
Histopathologic assessment of 273 non-desmoplastic medulloblastomas (MBs) from children aged 3 to 16 years and entered into the SIOP/UKCCSG (International Society of Pediatric Oncology/United Kingdom Children's Cancer Study Group) PNET3 trial revealed that 47 (17%) fulfilled criteria for the recently proposed anaplastic variant. In addition, an anaplastic phenotype was focally present in all 5 (2%) large cell MBs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.