Article
Characterization of EIAV LTR variability and compartmentalization in various reservoir tissues of long-term inapparent carrier ponies.
Virology - 20 Jun 2003
Reis Jenner K P, Craigo Jodi K, Cook Sheila J, Issel Charles J, Montelaro Ronald C
Abstract excerpt
Dynamic genomic variation resulting in changes in envelope antigenicity has been established as a fundamental mechanism of persistence by equine infectious anemia virus (EIAV), as observed with other lentiviruses, including HIV-1. In addition to the reported changes in envelope sequences, however, certain studies indicate the viral LTR as a second variable EIAV gene, with the enhancer region being designated as...
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