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Human Herpesvirus 7 Open Reading Frame U12 Encodes a Functional β-Chemokine Receptor

26 Jun 2003

Abstract excerpt

Human herpesvirus 6 (HHV- 6), which belongs to the betaherpesvirus subfamily and infects mainly T cells in vitro, causes acute and latent infections. HHV- 6 contains two genes (U12 and U51) that encode putative homologs of cellular G-protein-coupled receptors (GCR), while three other betaherpesviruses, human cytomegalovirus, murine cytomegalovirus, and human herpesvirus 7, have three, one, and two GCR-homologous...

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PMID: 12829849
DOI: 10.1128/jvi.77.14.8108-8115.2003

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