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Human Herpesvirus 6 Open Reading Frame U83 Encodes a Functional Chemokine

1 Jul 1999

Abstract excerpt

Some viruses including herpesviruses have undergone evolution to benefit viral infection and propagation by pirating and modifying host genes such as chemokine genes. Human herpesvirus 6 (HHV-6), acutely or persistently infects mononuclear cells in vitro. DNA sequence analysis of HHV-6 has revealed that the putative protein encoded by an open reading frame (ORF) of the U83 gene in HHV-6 variant B resembled a...

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PMID: 10364345
DOI: 10.1128/jvi.73.7.5926-5933.1999

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