Article
Structural analysis of the Kaposi's sarcoma-associated herpesvirus K1 protein.
Journal of virology - 1 Jul 2003
Lee Bok-Soo, Connole Michelle, Tang Zuoquin, Harris Nancy L, Jung Jae U
Abstract excerpt
The K1 protein of Kaposi's sarcoma-associated herpesvirus (KSHV) efficiently transduces extracellular signals to elicit cellular activation events through its cytoplasmic immunoreceptor tyrosine-based activation motif (ITAM). In addition, the extracellular domain of K1 demonstrates regional homology with the immunoglobulin (Ig) family and contains conserved regions (C1 and C2) and variable regions (V1 and V2). To...
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