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Identification and Analysis of the K5 Gene of Kaposi's Sarcoma-Associated Herpesvirus

15 Mar 2000

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8 (HHV-8), belongs to the gammaherpesvirus subfamily and encodes approximately 80 open reading frames (ORFs). Among them are a few candidates for immediate-early genes (e.g., K5). We developed a monoclonal antibody (MAb), 328C7, against the K5 antigen. This MAb reacted with the K5 gene product by immunoscreening of a cDNA library from BCBL-1...

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PMID: 10684303
DOI: 10.1128/jvi.74.6.2867-2875.2000

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