Article
Sendai virus targets inflammatory responses, as well as the interferon-induced antiviral state, in a multifaceted manner.
Journal of virology - 1 Jul 2003
Strähle Laura, Garcin Dominique, Le Mercier Philippe, Schlaak Joerg F, Kolakofsky Daniel
Abstract excerpt
We have used cDNA arrays to compare the activation of various cellular genes in response to infection with Sendai viruses (SeV) that contain specific mutations. Three groups of cellular genes activated by mutant SeV infection, but not by wild-type SeV, were identified in this way. While some of these genes are well known interferon (IFN)-stimulated genes, others, such as those for interleukin-6 (IL-6) and IL-8,...
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