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Article

Incidence and clinicobiologic characteristics of leukemic B-cell chronic lymphoproliferative disorders with more than one B-cell clone.

Blood - 15 Oct 2003

Sanchez Maria-Luz, Almeida Julia, Gonzalez David, Gonzalez Marcos, Garcia-Marcos Maria-Antonia, Balanzategui Ana, Lopez-Berges Maria-Consuelo, Nomdedeu Josep, Vallespi Teresa, Barbon Marcos, Martin Alejandro, de la Fuente Pilar, Martin-Nuñez Guillermo, Fernandez-Calvo Javier, Hernandez Jesus-Maria, San Miguel Jesus F, Orfao Alberto

Abstract excerpt

Leukemic B-chronic lymphoproliferative disorders (B-CLPDs) are generally believed to derive from a monoclonal B cell; biclonality has only occasionally been reported. In this study, we have explored the incidence of B-CLPD cases with 2 or more B-cell clones and established both the phenotypic differences between the coexisting clones and the clinicobiologic features of these patients. In total, 53 B-CLPD cases...

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Identifiers

PMID: 12829608
DOI: 10.1182/blood-2003-01-0045

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Source receipt: pubmed, retrieved 7 Sept 2026.

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