Article
Sibling familial risk ratio of meningococcal disease in UK Caucasians.
Epidemiology and infection - 1 Jun 2003
Haralambous E, Weiss H A, Radalowicz A, Hibberd M L, Booy R, Levin M
Abstract excerpt
To quantify the host genetic component of meningococcal disease (MD) susceptibility, the sibling risk ratio (lambdaS) was calculated as the ratio of observed MD cases among 845 siblings of 443 UK Caucasian cases to that expected, calculated from age-calendar year specific rates for England and Wales. Twenty-seven siblings contracted MD compared with an expected 0.89, generating a lambdaS value of 30.3....
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