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Article

Gastrointestinal stromal tumors (GIST): a model for molecule-based diagnosis and treatment of solid tumors.

Cancer science - 1 Apr 2003

Kitamura Yukihiko, Hirota Seiichi, Nishida Toshirou

Abstract excerpt

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the human gastrointestinal (GI) tract. The c-kit receptor tyrosine kinase (KIT) is expressed by practically all GISTs, and gain-of-function mutations of KIT are present in most GISTs. Interstitial cells of Cajal (ICC) a...

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Source

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Identifiers

PMID: 12824897
DOI: 10.1111/j.1349-7006.2003.tb01439.x
PMCID: PMC11160165

Genes

KIT
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12824897-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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