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Article

RevTrans: Multiple alignment of coding DNA from aligned amino acid sequences.

Nucleic acids research - 1 Jul 2003

Wernersson Rasmus, Pedersen Anders Gorm

Abstract excerpt

The simple fact that proteins are built from 20 amino acids while DNA only contains four different bases, means that the 'signal-to-noise ratio' in protein sequence alignments is much better than in alignments of DNA. Besides this information-theoretical advantage, protein alignments also benefit from the information that is implicit in empirical substitution matrices such as BLOSUM-62. Taken together with the...

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Identifiers

PMID: 12824361
DOI: 10.1093/nar/gkg609
PMCID: PMC169015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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