Article
Mapping a locus for familial thoracic aortic aneurysms and dissections (TAAD2) to 3p24-25.
Circulation - 1 Jul 2003
Hasham Sumera N, Willing Marcia C, Guo Dong-chuan, Muilenburg Ann, He Rumin, Tran Van T, Scherer Steven E, Shete Sanjay S, Milewicz Dianna M
Abstract excerpt
BACKGROUND: Familial thoracic aortic aneurysms and dissections (TAAD) occur as part of known syndromes such as Marfan syndrome but can also be inherited in families in an autosomal dominant manner as an isolated condition. Previous studies have mapped genes causing nonsyndromic familial TAAD to 5q13-15 (TAAD1) and 11q23.2-q24 (FAA1). Further genetic heterogeneity for the condition was evident by the presence of...
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