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Article

Plasminogen activator inhibitor 1 4G/5G polymorphism and coagulation factor XIII Val34Leu polymorphism: impaired fibrinolysis and early pregnancy loss.

Clinical chemistry - 1 Jul 2003

Dossenbach-Glaninger Astrid, van Trotsenburg Michael, Dossenbach Martin, Oberkanins Christian, Moritz Anne, Krugluger Walter, Huber Johannes, Hopmeier Pierre

Abstract excerpt

BACKGROUND: A successful outcome of pregnancy depends on proper placental formation. In the very beginning of this process, trophoblast invasion and fibrin deposition into the wall of the decidual veins play an important part. Two polymorphisms, coagulation factor XIII (FXIII) Val34Leu and plasminogen activator inhibitor 1 (PAI-1) 4G/5G, interfere with fibrin cross-linking and regulation of fibrinolysis and may...

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PMID: 12816904
DOI: 10.1373/49.7.1081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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