Article
Genotype and allele frequencies of TPMT, NAT2, GST, SULT1A1 and MDR-1 in the Egyptian population.
British journal of clinical pharmacology - 1 Jun 2003
Hamdy Samar I, Hiratsuka Masahiro, Narahara Kaori, Endo Naomi, El-Enany Mervat, Moursi Nadia, Ahmed Mohammed S-E, Mizugaki Michinao
Abstract excerpt
AIMS: The goal of this study was to determine the frequencies of important allelic variants in the TPMT, NAT2, GST, SULT1A1 and MDR-1 genes in the Egyptian population and compare them with the frequencies in other ethnic populations. METHODS: Genotyping was carried out in a total of 200 unrelated Egyptian subjects. TPMT*2 was detected using an allele-specific polymerase chain reaction (PCR) assay. TPMT*3C and...
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