Characterization of LytH, a differentiation-associated peptidoglycan hydrolase of Bacillus subtilis involved in endospore cortex maturation.

Abstract excerpt

The cortex peptidoglycan from endospores of Bacillus subtilis is responsible for the maintenance of dormancy. LytH (YunA) has been identified as a novel sporulation-specific component with a role in cortex structure determination. The lytH gene was expressed only during sporulation, under the control of the mother cell-specific sigma factor sigma(K). Spores of a lytH mutant have slightly reduced heat resistance...

Topics

• Bacillus subtilis
• Bacterial Proteins
• Gene Expression Regulation, Bacterial
• Heat-Shock Response
• Hot Temperature
• Microscopy, Electron
• Mutation
• N-Acetylmuramoyl-L-alanine Amidase
• Peptidoglycan
• Spores, Bacterial