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Article

Dentatorubral-pallidoluysian atrophy protein is phosphorylated by c-Jun NH2-terminal kinase.

Human molecular genetics - 1 Jul 2003

Okamura-Oho Yuko, Miyashita Toshiyuki, Nagao Kazuaki, Shima Seigo, Ogata Yukie, Katada Toshiaki, Nishina Hiroshi, Yamada Masao

Abstract excerpt

Dentatorubral-pallidoluysian atrophy (DRPLA) is a dominant-inherited neurodegenerative disease characterized by selective cell loss in particular neuronal pathways. This is caused by expansion of CAG repeats in the coding region of the DRPLA gene, and the extended polyglutamine tract (polyQ) confers a toxic activity. It is valuable to characterize disease gene products for elucidation of the mechanism underlying...

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PMID: 12812981
DOI: 10.1093/hmg/ddg168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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