Article
Milestones in cystic fibrosis.
British medical bulletin - 1 Oct 1992
Super M
Abstract excerpt
The study of cystic fibrosis (CF) provides a fascinating insight into developments in medicine in the 20th century. Milestones include the first clear clinical descriptions in the 1930s, discovery of a sweat electrolyte abnormality, establishing the autosomal recessive mode of inheritance and improvements in treatment. Microdissection experiments on sweat glands allowed the main defect to be delineated as one of...
Topics
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Genetic Therapy
- Genotype
- History, 20th Century
- Humans
- Membrane Proteins
- Phenotype